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Статья
2022

Synthesis, Alpha-Glucosidase Inhibition and Antibacterial Activities of the New Chiral (R)-3,3′-Disubstituted BINOL-Phosphates


Yesuraju KondaYesuraju Konda, Ashok Reddy AnkireddyAshok Reddy Ankireddy, Vani Madhuri VelavalapalliVani Madhuri Velavalapalli, Kalyani PaidikondalaKalyani Paidikondala, Aparna PasulaAparna Pasula, Rambabu GundlaRambabu Gundla
Российский журнал общей химии
https://doi.org/10.1134/S1070363222050206
Abstract / Full Text

A new class of 3,3′-disubstituted chiral (R)-BINOL-derived phosphoric acid derivatives has been prepared. The synthetic method has been optimized by involving Pd/C as a catalyst in the Suzuki–Miyaura cross coupling using a non-protected BINOL derivative. The target compounds have been characterized and tested for their α-glucosidase inhibitory and antibacterial activities.

Author information
  • Department of Chemistry, Jawaharlal Nehru Technological University, Hyderabad, 500085, Telangana, IndiaYesuraju Konda & Aparna Pasula
  • Department of Chemistry, GITAM Deemed to be University, Hyderabad, 502329, Telangana, IndiaAshok Reddy Ankireddy, Vani Madhuri Velavalapalli & Rambabu Gundla
  • Department of Chemistry, KG Reddy College of Engineering and Technology, Hyderabad, 501504, Telangana, IndiaKalyani Paidikondala
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