Статья
2021
Synthesis of New Diaryl(hetaryl)ethylphosphonic Acids
Yu. M. Sadykova, A. V. Zalaltdinova, А. K. Smailov, А. R. Burilov, М. А. Pudovik
Российский журнал общей химии
https://doi.org/10.1134/S1070363221070215
Abstract / Full Text
An original, new method for the synthesis of previously unknown diaryl(hetaryl)ethylphosphonic acids containing pharmacophoric fragments was developed as a result of the acid-catalyzed reaction of (2-ethoxyvinyl)phosphonic dichloride with heterocyclic compounds such as 4-hydroxy-6-methyl-2-pyrone, 4-hydroxycoumarin, and also thymol and carvacrol containing a hydroxyl group. Composition and structure of all diaryl(hetaryl)ethylphosphonic acids were confirmed according to 1H, 13С and 31P NMR, IR spectroscopy, mass spectrometry and elemental analysis data.
Author information
- Arbuzov Institute of Organic and Physical Chemistry, Federal Research Center “Kazan Scientific Center of the Russian Academy of Sciences”, 420088, Kazan, RussiaYu. M. Sadykova, А. R. Burilov & М. А. Pudovik
- Kazan National Research Technological University, 420015, Kazan, RussiaA. V. Zalaltdinova & А. K. Smailov
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