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Статья
2020

New complexes of pectic polysaccharides with nonsteroidal anti-inflammatory drugs


Y. V. ChekunkovY. V. Chekunkov, S. T. MinzanovaS. T. Minzanova, A. V. KhabibullinaA. V. Khabibullina, D. M. ArkhipovaD. M. Arkhipova, L. G. MironovaL. G. Mironova, A. V. NemtarevA. V. Nemtarev, A. R. KhamatgalimovA. R. Khamatgalimov, A. T. GubaidullinA. T. Gubaidullin, V. A. MilyukovV. A. Milyukov
Российский химический вестник
https://doi.org/10.1007/s11172-020-2801-z
Abstract / Full Text

The formation of stable complexes of citrus pectin with nonsteroidal anti-inflammatory drugs, ibuprofen and acetylsalicylic acid (aspirin), was confirmed by IR and NMR spectro scopy. The stoichiometry of complexes with the maximum content of drugs (15 wt. %) was established. A comparative study of the thermal decomposition of pectin and the synthesized complexes with ibuprofen and acetylsalicylic acid was performed by TG/DSC.

Author information
  • A. E. Arbuzov Institute of Organic and Physical Chemistry, Federal Research Center “Kazan Scientific Center of the Russian Academy of Sciences,”, 8 ul. Akad. Arbuzova, 420088, Kazan, Russian FederationY. V. Chekunkov, S. T. Minzanova, A. V. Khabibullina, D. M. Arkhipova, L. G. Mironova, A. V. Nemtarev, A. R. Khamatgalimov, A. T. Gubaidullin & V. A. Milyukov
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