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Статья
2012

Efficacy of an Intervention for Families Living with HIV in Thailand: A Randomized Controlled Trial


Li LiLi Li, Li-Jung LiangLi-Jung Liang, Mary Jane Rotheram-BorusMary Jane Rotheram-Borus
AIDS and Behavior
https://doi.org/10.1007/s10461-011-0077-x
Abstract / Full Text

This study evaluates the efficacy of an intervention for persons living with HIV (PLH) and their family members in Thailand. A randomized controlled trial of 813 PLH and family members was carried out at four district hospitals in Thailand. Participants completed Computer Assisted Personal Interview assessments at baseline, 6, 12, 18, and 24 months. The primary outcome was quality of life (QoL); other measures included depressive symptoms and family functioning. Relative to the standard care condition, the intervention group reported significantly improved QoL at 6 months (P = 0.0014). When the intervention efficacy was stratified by baseline depressive symptoms (low vs. high), intervention efficacy was observed only among those with low depressive symptoms. Study findings suggest that the intervention was more efficacious for participants with less depressive symptoms and better family functioning. Extensive interventions may be optimal for those who have the capacity to learn the tools and skills.

Author information
  • Semel Institute for Neuroscience and Human Behavior, Center for Community Health, University of California at Los Angeles, 10920 Wilshire Blvd., Suite 350, Los Angeles, CA, 90024, USALi Li, Sung-Jae Lee, Dai Wan & Mary Jane Rotheram-Borus
  • Department of Medicine Statistics Core, University of California at Los Angeles, Los Angeles, CA, USALi-Jung Liang
  • Bureau of Epidemiology, Thai Ministry of Public Health, Bangkok, ThailandSopon Iamsirithaworn
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