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Статья
2020

Synthesis of Some Indolyl Derivatives under Solvent Free Conditions, Their Cytotoxicity, and DNA Cleavage Studies


A. S. RathodA. S. Rathod, J. S. BiradarJ. S. Biradar
Российский журнал общей химии
https://doi.org/10.1134/S1070363220010211
Abstract / Full Text

A one-pot, rapid, facile, green, and efficient method of synthesis of pyran fused indolyl and 1,3-dicarbonyl analogs has been carried out under the conventional and also solvent-free conditions involving MW irradiation. The structures of products have been confirmed by spectral data. All products have been tested for DNA cleavage and in vitro cytotoxicity against three tumor cell lines. Some products are characterized by high activity.

Author information
  • Central Research Lab, Department of Chemistry, Gulbarga University, Kalaburagi, Karnataka, 585106, IndiaA. S. Rathod & J. S. Biradar
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