Electrochemical Sensing of Uric Acid Using a ZnO/Graphene Nanocomposite Modified Graphite Screen Printed Electrode

Rasoul Rezaei Rasoul Rezaei , Mohammad Mehdi Foroughi Mohammad Mehdi Foroughi , Hadi Beitollahi Hadi Beitollahi , Reza Alizadeh Reza Alizadeh
Российский электрохимический журнал
Abstract / Full Text

An electrochemical sensor has been fabricated using ZnO/GR nanocomposite for selective determination of uric acid (UA) in a phosphate buffer solution (PBS, pH 7.0). The electrochemical behaviour of UA at the ZnO/GR nanocomposite modified graphite screen printed electrodes (SPE) was studied by cyclic voltammetry and differential pulse voltammetry methods. The modified electrode exhibited remarkably anodic peak corresponding to the oxidation of uric acid over the concentration range of 1.0–100.0 μM with detection limit of 0.43 μM (S/N = 3). The fabricated sensor was further applied to the detection of uric acid in urine samples with good selectivity and high reproducibility.

Author information
  • Department of Chemistry, Faculty of Sciences, Islamic Azad University, Kerman Branch, Kerman, Iran

    Rasoul Rezaei & Mohammad Mehdi Foroughi

  • Environment Department, Institute of Science and High Technology and Environmental Sciences, Graduate University of Advanced Technology, Kerman, Iran

    Hadi Beitollahi

  • Department of Chemistry, Faculty of Science, Qom University, Qom, Iran

    Reza Alizadeh

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