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Статья
2021

One Pot, Four-Component, and Green Synthesis of Novel 2-(2-Amino-7,7-dimethyl-5-oxo-4-phenyl-5,6,7,8-tetrahydro-4H-chromene-3-carbonyl)-2,3-dihydrophthalazine-1,4-dione Derivatives


M. V. SatyanarayanaM. V. Satyanarayana, A. G. ReddyA. G. Reddy, J. SandhyaJ. Sandhya, B. K. MehtaB. K. Mehta, K. R. S. PrasadK. R. S. Prasad, M. Bhuvan TejM. Bhuvan Tej, M. V. Basaveswara RaoM. V. Basaveswara Rao
Российский журнал общей химии
https://doi.org/10.1134/S1070363221070185
Abstract / Full Text

An efficient one pot, four-component and green synthesis of novel 2-(2-amino-7,7-dimethyl-5-oxo-4-phenyl-5,6,7,8-tetrahydro-4H-chromene-3-carbonyl)-2,3-dihydrophthalazine-1,4-dione derivatives has been developed by condensing dimethyl phthalate 1 with 2-cyanoacetohydrazide, benzaldehydes and 5,5-dimethylcyclohexane-1,3-dione using L-proline as a catalyst in ethanol. Pure products are obtained in high yields without column chromatography involved. The method is environmentally friendly, simple and proceeds under mild reaction conditions.

Author information
  • Department of Chemistry, Koneru Lakshmaiah Education Foundation, Green Fields, Vaddeswaram, Andhra Pradesh, 522502, Guntur, IndiaM. V. Satyanarayana & K. R. S. Prasad
  • Department of Pharmacy, Sana College of Pharmacy, Kodad, 508206, Telangana, IndiaA. G. Reddy
  • Department of Chemistry, Vaageswari College of Engineering, Karimnagar, 505001, Telangana, IndiaJ. Sandhya
  • Department of Chemistry, National Defense Academy, Pune, 508206, Maharashtra, IndiaB. K. Mehta
  • Sri Ramachandra Medical College and Research Institute, Porur, Chennai, 600116, Tamilnadu, IndiaM. Bhuvan Tej
  • Department of Chemistry, Krishna University, Andhra Pradesh, 521003, Machilipatnam, IndiaM. V. Basaveswara Rao
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