Статья
2021
One Pot, Four-Component, and Green Synthesis of Novel 2-(2-Amino-7,7-dimethyl-5-oxo-4-phenyl-5,6,7,8-tetrahydro-4H-chromene-3-carbonyl)-2,3-dihydrophthalazine-1,4-dione Derivatives
M. V. Satyanarayana, A. G. Reddy, J. Sandhya, B. K. Mehta, K. R. S. Prasad, M. Bhuvan Tej, M. V. Basaveswara Rao
Российский журнал общей химии
https://doi.org/10.1134/S1070363221070185
Abstract / Full Text
An efficient one pot, four-component and green synthesis of novel 2-(2-amino-7,7-dimethyl-5-oxo-4-phenyl-5,6,7,8-tetrahydro-4H-chromene-3-carbonyl)-2,3-dihydrophthalazine-1,4-dione derivatives has been developed by condensing dimethyl phthalate 1 with 2-cyanoacetohydrazide, benzaldehydes and 5,5-dimethylcyclohexane-1,3-dione using L-proline as a catalyst in ethanol. Pure products are obtained in high yields without column chromatography involved. The method is environmentally friendly, simple and proceeds under mild reaction conditions.
Author information
- Department of Chemistry, Koneru Lakshmaiah Education Foundation, Green Fields, Vaddeswaram, Andhra Pradesh, 522502, Guntur, IndiaM. V. Satyanarayana & K. R. S. Prasad
- Department of Pharmacy, Sana College of Pharmacy, Kodad, 508206, Telangana, IndiaA. G. Reddy
- Department of Chemistry, Vaageswari College of Engineering, Karimnagar, 505001, Telangana, IndiaJ. Sandhya
- Department of Chemistry, National Defense Academy, Pune, 508206, Maharashtra, IndiaB. K. Mehta
- Sri Ramachandra Medical College and Research Institute, Porur, Chennai, 600116, Tamilnadu, IndiaM. Bhuvan Tej
- Department of Chemistry, Krishna University, Andhra Pradesh, 521003, Machilipatnam, IndiaM. V. Basaveswara Rao
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