Article
2021

Immobilization of an Antibacterial Compound from Streptomyces sp. onto Multi-Walled Carbon Nanotubes


 Jannu Vinay Gopal Jannu Vinay Gopal , Modigunta Jeevan Kumar Reddy Modigunta Jeevan Kumar Reddy , Krishnan Kannabiran Krishnan Kannabiran
Russian Journal of Electrochemistry
https://doi.org/10.1134/S1023193521010043
Abstract / Full Text

The pigment compound 2,5-di-tert-butyl-1,4-benzoquinone (DTBBQ) was selectively immobilized on multi-walled carbon nanotube (MWNT) during the electrochemical oxidation process. The glassy carbon electrode (GCE)/Q/MWNT showed a stable redox peak at 50 mV vs. Ag/AgCl in pH 7. Antibacterial activity of DTBBQ immobilized on multi-walled nanotube (hybrid DTBBQ/MWNT) against Bacillus cereus (MTCC 1168) and Escherichia coli (MTCC 2401) showed an enhanced minimum inhibitory concentration at 0.78 and 1.5 µg/mL against the bacterial pathogens. The results evidently show the immobilization of DTBBQ on CNT with enhanced redox response peaks observed at –0.01 V (Epa) and –0.2V (Epc) vs. Ag/AgCl. This new electrochemical method to immobilize the drugs onto MWNT is successfully demonstrated and would have potential applications as a remedy for removal of harmful microbes from the environment.

Author information
  • Sun-yatsen University, School of Marine Science, Guangzhou, China

    Jannu Vinay Gopal

  • Department of Polymer Science and Engineering, Department of IT Convergence, Korea National University of Transportation, 23769, Chungju, South Korea

    Modigunta Jeevan Kumar Reddy

  • Vellore Institute of Technology, School of Biosciences and Technology, 632014, Vellore, India

    Krishnan Kannabiran

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